image: the two functions of sulforaphane uncovered by the current study are; 1) ameliorating obesity by adipose tissue browning to augment energy consumption and 2) improving 'high-fat' gut bacterial flora and... view more credit: kanazawa university[background]sulforaphane*1, a phytochemical contained in broccoli sprouts at relatively high concentrations, has been known to exert effects of cancer prevention by activating a transcription factor, nrf2 (nuclear factor (erythroid-derived 2)-like 2), which regulates the balance of oxidation - reduction in the cell, and by enhancing anti-oxidation ability of the body and detoxication of chemical compounds taken into the body. on the other hand, when the balance of oxidation - reduction is deteriorated due to hyper nutrition and obesity, it has been known to be related to pathogenesis of various diseases. the effects of sulforaphane on obesity were, however, unclear. [results]in the current study, the researchers of kanazawa university in collaboration with the researchers of kagome co., ltd. compared the mice fed with high-fat food supplemented with sulforaphane and the others with high-fat food but without sulforaphane in terms of their body weight. the researchers found that the mice fed with sulforaphane exhibited the weight gain rate 15% lower than that of the mice fed without sulforaphane, 20% visceral fat reduction, and...