Laxaro Your source for the latest research news
 building and breaking connections how neuronal networks influence alcoholism
building and breaking connections: how neuronal networks influence alcoholism

IMAGE: This is Jun Wang, MD, PhD, assistant professor at the Texas A&M College of Medicine.
view more Credit: Texas A&M University Health Science CenterAbout 15.1 million American adults have alcohol use disorder, meaning they cannot stop drinking despite adverse consequences--in other words, they have what is commonly referred to as alcoholism. Although it has been known that alterations in the connections between neurons in the brain likely play a role in alcohol dependence and other addictions, the cause-and-effect between these brain alterations and behavior has been less clear.Now, Texas A&M research indicates that alcohol-seeking behavior may be induced by altering the strength of connections between particular neurons, according to recent results published in the journal Nature Ne

umd exercise study offers hope in fight against alzheimer's

IMAGE: The brain's posterior cingulate cortex (PCC)/precuneus region is a hub of neuronal networks which integrates and disperses signals. A loss of connectivity to this hub is associated with memory loss...
view more Credit: J. Carson SmithCould the initiation of a simple walking exercise program help older adults to reverse declines in key brain regions? A new study led by University of Maryland School of Public Health researchers adds more information about how physical activity impacts brain physiology and offers hope that it may be possible to reestablish some protective neuronal connections. Dr. J. Carson Smith, associate professor of kinesiology, and colleagues explored how a 12-week walking intervention with older adults, ages 60-88, affected functionality of a brain region known

accommodating workers with a history of substance abuse

Employers don't have to accommodate any alcohol or illicit drug use in the workplace, but they must be careful not to discriminate against workers with a history of substance abuse who are no longer using.The Americans with Disabilities Act (ADA) protects workers from discrimination based on a qualifying disability or a perceived disability—including alcoholism and past illegal drug use, explained Todd Wulffson, an attorney with Carothers DiSante & Freudenberger in Orange County, Calif. Therefore, employers should try to arrange a reasonable accommodation if, for example, an employee needs to leave early for an Alcoholics Anonymous meeting, Wulffson explained. The ADA covers businesses with 15 or more employees and protects workers with a history of illicit drug use who:Have successfully b

wifi connections in dutch inner cities get worse, it's a connection jungle

Photo: Depositphotos.comAlmost 40% of wifi connections in Dutch inner cities are poor because so many networks are competing with each other, according to a new report by the government’s telecoms agency.Two years ago, 27% of connections could be described as poor, the agency is quoted as saying by the NRC.Most domestic wifi services use the overcrowded 2.4 GHz bandwidth, which also hosts bluetooth appliances such as doorbells. In addition, the spectrum is becoming increasingly busy due to the popularity of live streaming.The agency measured the quality of wifi connections in some 200 places. ‘In places where reception was bad, it is now worse,’ said spokesman Paul Wijninga in the NRC.The problem is particularly acute in older houses – newer homes are better insulated against interference

wifi connections in dutch inner cities gets worse, it's a connection jungle

Photo: Depositphotos.comAlmost 40% of wifi connections in Dutch inner cities are poor because so many networks are competing with each other, according to a new report by the government’s telecoms agency.Two years ago, 27% of connections could be described as poor, the agency is quoted as saying by the NRC.Most domestic wifi services use the overcrowded 2.4 GHz bandwidth, which also hosts bluetooth appliances such as door bells. In addition, the spectrum is becoming increasingly busy due to the popularity of live streaming.The agency measured the quality of wifi connections in some 200 places. ‘In places where reception was bad, it is now worse,’ said spokesman Paul Wijninga in the NRC.The problem is particularly acute in older houses – newer homes are better insulated against interference

young men are dying of alcoholism in russia's far east

Seventy percent of deaths among men under 35 in Russia's Far East are due to alcohol-related causes, the country’s chief health official warned on Wednesday.While chronic alcoholism and alcohol-related psychosis affect 60 out of every 100,000 Russians on average, “The average figure for the Far Eastern District is more than 120 [per 100,000],” Health Minister Veronika Skvortsova was cited as saying by the RBC business outlet at the Eastern Economic Forum in Vladivostok.The autonomous Chukotka district is an outlier where there are 330 victims of alcoholism for every 100,000 people, she said. 

multiple ant-like transport of neuronal cargo by motor proteins

Cargo transport by many motors makes neuronal activity fine. Credit: Kumiko HayashiMicrotubules are roads made of proteins that extend throughout a cell for motor proteins (carriers) to deliver neuronal cargo packed with many kinds of materials required for cellular activity. The delivery is active along neuronal axons, which function like highways in human societies. Deficits in the supply chain cause neuronal diseases, such as Alzheimer's, Parkinson's or Huntington's disease.
Dr. Kumiko Hayashi and Dr. Shinsuke Niwa, assistant professors of Tohoku University, have successfully estimated the force exerted by motor proteins acting on neuronal cargo in living worms using a newly developed, noninvasive force measurement method (Ref. 1). The force values indicate that a number of carriers a

multiple ant-like transport of neuronal cargo by motor proteins

IMAGE: Cargo transport by many motors makes neuronal activity fine.
view more Credit: Kumiko HayashiMicrotubules (roads made of proteins) extend throughout a cell for motor proteins (carriers) to deliver neuronal cargo packed with many kinds of materials required for life activity. The delivery is active along neuronal axons, which function like highways in human societies. Deficits in the cargo delivery cause neuronal diseases, such as Alzheimer's, Parkinson's or Huntington's disease. Dr. Kumiko Hayashi and Dr. Shinsuke Niwa, assistant professors of Tohoku University, have successfully estimated the force exerted by motor proteins acting on neuronal cargo in living worms using a newly developed non-invasive force measurement method (Ref. 1). The force values indicate that a number of ca

'friends of friends' relationships may be simpler than they seem

Social network between simulated individuals. The circles denote individuals and the black lines show interactions between them. The red circles denote those which mainly interact with their own group members and the blue circles show those which mainly interact with others. Credit: Oxford UniversityNot only are immediate friendships an important aspect of our life, but so are our extended acquaintances and friends' of friends connections, according to new Oxford University research. The findings shed light on how social networks can evolve, by showing that complex social patterns observed across the animal kingdom may be simpler than they appear.
These relationships are known as 'indirect social connections," and show where each individual is positioned within the overall social network

the extent of neuronal loss in the brain during ms

A study by researchers from Queen Mary University of London establishes for the first time the extent of neuronal loss in the brain of a person with MS over their life, and finds that demyelination may not be as good an indicator of disease progression as previously thought.By dissecting and analysing brains from nine people with MS and seven healthy controls using gold standard techniques, they found that the mean number of neurons was 14.9 billion in MS versus 24.4 billion in controls - a 39% difference. The density of neurons in MS was smaller by 28%, and cortical volume by 26%, and they found that the whole brain was affected equally.Importantly, the number of neurons was strongly associated with the thickness of the cortex, which is something that can be measured by MRI. The decline i

academic performance shapes student social networks

Credit: Vilem Skarolek/public domainBased on data from the VKontakte social network, researchers at Higher School of Economics and the Vienna Medical University have found a relationship between students' academic performance and their closest social environment. The study results were published in PLOS ONE.
People's tendency to network socially with those who share their characteristics is one of the key driving forces in building and shaping social connections.Academic achievement appears to be one of the areas in which similarities lead to connections. There are two main reasons why friends tend to have similar academic performance. First, they can influence one another academically, e.g. by helping friends who struggle in class. Second, they may choose peers with similar academic per

hdac6 inhibitors protect against neuronal damage and have therapeutic potential

Inhibiting HDAC6 improves the structural stability of cells and protects against neuronal damage. Leuven research uncovered that targeting this mechanism could be a promising therapeutic approach for peripheral neuropathies, whether due to Charcot-Marie-Tooth disease (CMT) or as a side effect of chemotherapy.
Histone deacetylase 6, HDAC6 in short, deacetylates α-tubulin, one of the main structural components of the cytoskeleton. Tubulin is a building block for the cellular tracks that guide the delivery of cargoes, such as mitochondria and vesicles, across the cell. These building blocks can be modified chemically, for example by acetylation, to allow for further fine-tuning of the cytoskeletal stability. This is important, especially in the long axons of human motor neurons and sensory n

presstv-hollywood and morality

Why is alcoholism so widely promoted in the American culture? Would it be fair to say that heavy drinking is encouraged by Hollywood or is it just the pop culture being reflected in the movies?Is smoking advertised by Hollywood? Can Hollywood be blamed for tobacco-related deaths? Is Hollywood basically publicizing smoking and alcoholism? Can the illustration of cigarette smoking, drug abuse and alcohol consumption be the main reason why young audiences are leaning towards these habits?

alcoholism may be caused by dynamical dopamine imbalance

Researchers from the Higher School of Economics, Ecole Normale Supérieure, Paris, Indiana University and the Russian Academy of Sciences Nizhny Novgorod Institute of Applied Physics have identified potential alcoholism mechanisms, associated with altered dopaminergic neuron response to complex dynamics of prefrontal cortex neurones affecting dopamine release.
Interacting neuronal populations in the cerebral cortex generate electrical impulses (called action potentials), that are characterized by specific spatial and temporal patterns of neural firing (or complex neural dynamics). These firing patterns depend on the intrinsic properties of individual neurones, on the neural network connectivity and the inputs to these circuits. Taken as a basis for this computational study is the experimen

wi-fi not working on your iphone or ipad? here's the fix!

If you're having trouble connecting to Wi-Fi with your iPhone or iPad, we've got the troubleshooting guide for you.In theory, wireless connections and cellular networks should live happily in harmony on your iPhone or iPad. Your device uses automatic switching technology to pop you on known Wi-Fi networks and send you back to cellular when you're out of range, and it works great... most of the time.But let's be honest: Wireless networks — especially those that have interstitial signup sheets — can be finicky. If you're running into problems with your Wi-Fi network on your iPhone or iPad, here are some good troubleshooting tips to try.1. Is your Wi-Fi even on, bro?Yes, this is a pretty straight-forward troubleshoot, but always worth checking: Have you accidentally disabled Wi-Fi or turned o

alzheimer's disease: neuronal loss very limited

Frequently encountered in the elderly, Alzheimer's is considered a neurodegenerative disease, which means that it is accompanied by a significant, progressive loss of neurons and their nerve endings, or synapses. A joint French and Canadian study published in Scientific Reports now challenges this view. Conducted among more than 170 subjects at various stages of Alzheimer's disease, the study by the team led by Salah El Mestikawy (Douglas Mental Health University Institute, Canada) and Stéphanie Daumas (Université Pierre et Marie Curie, France) has shown instead that the disease is accompanied by a minor decline in neuronal and synaptic markers."Much to our surprise, in studying the fate of eight neuronal and synaptic markers in our subjects' prefrontal cortices, we only observed very mino

predicting influencers has just been made simpler

Social networks, such as Twitter, thrive on key influencers spreading news. Like information, epidemics also spread from key individuals. To identify the most influential actors in such networks, many studies have, until now, focused on ranking the influence of individual nodes. But these methods are not accurate enough to single out influential spreaders because they fail to take into account the spreading dynamics.

'neuron-reading' nanowires could accelerate development of drugs for neurologica

A team led by engineers at the University of California San Diego has developed nanowires that can record the electrical activity of neurons in fine detail. The new nanowire technology could one day serve as a platform to screen drugs for neurological diseases and could enable researchers to better understand how single cells communicate in large neuronal networks.

android apps can find nearby devices even when they're offline

The kit supports both mesh networks, where devices form an independent network on the spot, as well as a centralized connection where one device rules the roost. That's particularly helpful in classrooms or meetings, where you'd want one device to take priority -- say, a Jackbox-style party game where a host hands out trivia questions.It'll take a while for the new Nearby Connections to wend its way into the apps you use, but there are already companies who've had a head start. The Weather Channel is installing mesh networks in areas with poor internet access to help send weather warnings, Hotstar is offering offline media sharing and GameInsight will help you find and play people offline. And of course, Google has its own -- an upcoming Android TV remote app will use Nearby Connections to

tracking live brain activity with the new neubtracker open-source microscope

A team of scientists from the Helmholtz Zentrum München and the Technical University of Munich (TUM) has successfully developed a new type of microscope. The NeuBtracker is an open source microscope that can observe neuronal activities of zebrafish without perturbing their behavior. This is opening up completely new perspectives for science, because now it will be possible to track natural behavior while simultaneously imaging neuronal activity in the brain.

time for the old boys to make way for new girls

Old boys' clubs have been around for so long that they are officially part of our lexicon. What was once a phrase used solely to refer to school alumni is now synonymous with a network of men "regarded as prestigious or influential, whose members provide each other with assistance or preferential treatment".Look for a similar definition of old girls' clubs and your search will come up blank. The idea of a group of well-connected and influential women helping each other professionally is still so new that it has barely entered our dictionaries, let alone society. But one woman is hoping to change that.
It was only when I began to accidentally meet old girls through my work as a journalist that I began to understand the real benefits of networking. Photo: Sean LockeCheryl Giovannoni, chief

small streams have a big influence on our lives

Small streams make up 70%-80% of the total channel length of river networks, and they strongly influence downstream portions these networks. The role small streams ? known as headstreams ? play in retaining or transmitting sediment and nutrients, providing habitat and refuge for diverse aquatic and riparian organisms, creating migration corridors, and governing connectivity at the watershed-scale is the subject of a review by Ellen Wohl of Colorado State University in the US. The article is published in a special issue on Headwater Regions in the journal Frontiers of Earth Science, which is jointly published by Higher Education Press in China and Springer.
Historically, headwater streams have been given little attention by researchers, policy makers, and landowners. However, we now know

hierarchical opportunistic routing with moderate clustering for ad hoc networks

The self-organizing nature of ad hoc networks generally has an advantage that the networks are free from fixed infrastructures such as APs (Access points). However, this also has a disadvantage that the networks are unstable and unreliable compared with wired and fixed communication.

how developing visual system axons stay in the correct layer

IMAGE: During the pupal stage, photoreceptors extend the axons into the brain region called medulla which has layered structure. All the photoreceptor axons are labeled in red, and R7 photoreceptor axons...
view more Credit: Takashi SuzukiScientists at Tokyo Tech have made an important discovery concerning the development of layer-specific axonal connections in the developing visual system of Drosophila flies. This discovery provides valuable insights into how neurons in the developing brain are wired. The molecular mechanisms we found can serve as a universal principle for wiring axons also in higher animals. We assume our findings help stabilize the regenerating axons to the desired depth in the brain layers, in the case such as neuronal transplantation after injury.Drosophila flies, w

phd students

Department: IMDEA Networks
Institution: IMDEA Networks
IMDEA Networks Institute (www.networks.imdea.org) is a networking research organization whose multinational team is engaged in cutting edge fundamental science. As a growing, English-speaking institute located in Madrid, Spain, IMDEA Networks offers a unique opportunity for pioneering scientists to develop their ideas. IMDEA Networks is establishing itself internationally at the fo...
(Visit http://academickeys.com/r?job=99219&tag=99219-rss for the complete position description.)

Search Tags
flynn revelations is it nuts to vote on gorsuch during the russia scandal imore show 561 wwdc 2017 preview chaos and confusion labor led jurisdictions blast turnbull over emissions backdown language requirements latest oxygenos κουμουτσάκος aδιάλλακτη και αντιπαραγωγική η τουρκική πολιτική πολιτικές ειδήσεις الحشد الشعبي يحرر قرية عزيز شمال القيروان amazon pokes fun at glitches says tech gadgets popular cars getting metro means former canberra severe case stricter border during early bet on a consistent performer presstv israeli pm interrogated over corruption case term bonuses high sierra update в башкирии составили молочный рейтинг экономика деньги how to set up emby dvr could conceivably επιβατηγό πλοίο προσέκρουσε στο λιμάνι της σκιάθου σώοι οι επιβάτες κοινωνία blackbuck poaching case salman khan arrives in jodhpur for court hearing family shoe how vw s arteon keeps you alive if you pass out while driving leave under iisers tuition fee hiked from this year furukawa said greg gianforte wins montana house seat after assault charge τι προβλέπει το πολυνομοσχέδιο για την κυριακάτικη λειτουργία καταστημάτων πολιτική επικαιρότητα قطر تستنكر بيان منظمة التعاون الإسلامي وتعده متحيزا monday 20 august 2018 the week uk icebergs pool babakhani said management system credit michelle cbi nabs accused in 1993 bombing of rss chennai headquarter your transition yet another free voice silenced in gauri s murder
Facebook Twitter Google Plus Digg Share This

All rights reserved. © Laxaro 2016-2017 Run in 0.098 seconds