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 vaccination method that wiped out smallpox gets unleashed today on ebola
vaccination method that wiped out smallpox gets unleashed today on ebola

Enlarge/ Nurses working with the World Health Organization administer the Ebola vaccine to a local doctor at the town hall of Mbandaka on May 21, 2018 during the launch of the Ebola ont style="color:#666;background-color:#fff5a9;">vaccinationont> campaign. Getty | JUNIOR KANNAHShare this storyWith more than 7,500 doses of an experimental vaccine against Ebola, health officials ont style="color:#666;background-color:#fff5a9;">todayont> began a ont style="color:#666;background-color:#fff5a9;">vaccinationont> campaign to try to thwart the latest ont style="color:#666;background-color:#fff5a9;">outont>break of the deadly virus in the Democratic Republic of the Congo.According to the World Health Organization, the campaign will start with healthcare workers operating in areas affected by the ont style="color:#666;background-color:#fff5a9;">outont>break. Then officials will focus on a “ring ont style="color:#666;background-color:#fff5a9;">vaccinationont>” strategy, which taront style="color:#666;background-color:#fff5a9;">getsont> people who have had contact with someone with a confirmed case of Ebola, as well as people who have had contact with those contact

who supports ebola vaccination of high risk populations in the democratic republ

The Government of the Democratic Republic of Congo, with the support of WHO and partners, is preparing to vaccinate high risk populations against Ebola virus disease (EVD) in affected health zones.Health workers operating in affected areas are being vaccinated ont style="color:#666;background-color:#fff5a9;">todayont> and community ont style="color:#666;background-color:#fff5a9;">outont>reach has started to prepare for the ring ont style="color:#666;background-color:#fff5a9;">vaccinationont>.More than 7,500 doses of the rVSV-ZEBOV Ebola vaccine have been deployed to the Democratic Republic of the Congo to conduct ont style="color:#666;background-color:#fff5a9;">vaccinationont> in the northwestern Equator Province where 46 suspected, probable and confirmed Ebola cases and 26 deaths have been reported (as of May 18). Most of the cases are in Bikoro, a remote rural town, while four confirmed cases are in Mbandaka, the provincial capital with a population of over 1 million people.The vaccines are dona

mass vaccinations will not prevent ebolavirus outbreaks, new research shows

Prophylactic mass ont style="color:#666;background-color:#fff5a9;">vaccinationont> programmes are not a realistic option in the battle to prevent new Ebolavirus ont style="color:#666;background-color:#fff5a9;">outont>breaks, a University of Kent-led research team has shown.The findings come as the World Health Organisation has announced a new Ebola virus ont style="color:#666;background-color:#fff5a9;">outont>break in the Democratic Republic of Kongo. The team analysed the prospects for various Ebolavirus vaccines and found ont style="color:#666;background-color:#fff5a9;">thatont>, for the foreseable future at least, Ebolavirus ont style="color:#666;background-color:#fff5a9;">outont>break control depends on surveillance and the isolation of cases.The researchers' analysis revealed ont style="color:#666;background-color:#fff5a9;">thatont> very high proportions of potentially affected populations would need to be protected by ont style="color:#666;background-color:#fff5a9;">vaccinationont> to establish herd immunity, i.e. the level of immunity ont style="color:#666;background-color:#fff5a9;">thatont> prevents virus transmission within a population. The study, entitled Herd immunity to Ebolaviruses is not a

congo approves use of ebola vaccination to fight outbreak - democratic republic

The rVSV-ZEBOV vaccine developed by Merck is not yet licensed but was shown to be highly protective against Ebola in clinical trialsBy Aaron RossKINSHASA, May 29 (Reuters) - Democratic Republic of Congo's health ministry has approved the use of a new Ebola vaccine to counter an ont style="color:#666;background-color:#fff5a9;">outont>break in its northeast ont style="color:#666;background-color:#fff5a9;">thatont> has killed four people, a spokesman said on Monday.Read more on Thomson Reuters Foundation.

ebola vaccines provide immune responses after 1 year

Immune responses to Ebola vaccines at one year after ont style="color:#666;background-color:#fff5a9;">vaccinationont> are examined in a new study appearing in the March 14 issue of JAMA.The Ebola virus vaccine strategies evaluated by the World Health Organization in response to the 2014-2016 ont style="color:#666;background-color:#fff5a9;">outont>break in West Africa included a heterologous primary and booster ont style="color:#666;background-color:#fff5a9;">vaccinationont> schedule of the adenovirus type 26 vector vaccine encoding Ebola virus glycoprotein (Ad26.ZEBOV) and the modified vaccinia virus Ankara vector vaccine, encoding glycoproteins from Ebola, Sudan, Marburg, and Tai Forest viruses nucleoprotein (MVA-BN-Filo). These vaccines both used a 'viral-vector' approach, where a benign virus is modified to safely express key proteins of the target virus, in this case Ebola. This schedule has been shown to induce immune responses ont style="color:#666;background-color:#fff5a9;">thatont> persist

la guinée se bat contre une importante épidémie de rougeole - guinea

Moins d’un an après la fin officielle de l’épidémie Ebola, le système de santé guinéen continue de lutterConakry, 7 avril – L’organisation humanitaire internationale Médecins Sans Frontières (MSF) lance aujourd’hui une large campagne de ont style="color:#666;background-color:#fff5a9;">vaccinationont> contre la rougeole à Conakry, en collaboration avec le ministère de la Santé guinéen. Depuis le début de cette année, 3468 cas ont été confirmés et 14 décès ont été recensés suite à la rougeole dans tont style="color:#666;background-color:#fff5a9;">outont> le pays. Conakry et Nzérékoré sont les préfectures les plus affectées.La ont style="color:#666;background-color:#fff5a9;">vaccinationont> de ront style="color:#666;background-color:#fff5a9;">outont>ine en Guinée a été drastiquement réduite durant l’épidémie Ebola en 2014-2015, suite à l’allocation des ressources et de l’attention à la gestion de l’épidémie Ebola mais également en raison de la peur : les personnes sont restées à l’écart des centres d

congo approves use of ebola vaccination to fight outbreak - democratic republic

KINSHASA, May 29 (Reuters) - Democratic Republic of Congo's health ministry has approved the use of a new Ebola vaccine to counter an ont style="color:#666;background-color:#fff5a9;">outont>break of the hemorrhagic fever in its northeast ont style="color:#666;background-color:#fff5a9;">thatont> has killed four people, a spokesman said on Monday."The non-objection was given. Now there's a Medecins Sans Frontieres team ont style="color:#666;background-color:#fff5a9;">thatont> is arriving (in Congo) ont style="color:#666;background-color:#fff5a9;">todayont> to validate the protocol with the technical teams," Jonathan Simba, a health ministry spokesman, said by telephone.Read more on Reuters.

ebola found in large congo city raises major outbreak fears

Ebola, a virus ont style="color:#666;background-color:#fff5a9;">thatont> causes hemorrhagic fever, has appeared in a large city in the Democratic Republic of Congo, stoking fears of an ont style="color:#666;background-color:#fff5a9;">outont>break occurring in a densely populated region. The virus typically crops up in remote regions in Africa, but the World Health Organization reports ont style="color:#666;background-color:#fff5a9;">thatont> an ebola case was confirmed in Mbandaka, a city with a population of 1.2 million.Ebola’s containment to smaller, more rural regions helps prevent massive ont style="color:#666;background-color:#fff5a9;">outont>breaks. However, the 2014 ebola crisis resulted in the virus infecting individuals in a more populated region in West Africa, where abont style="color:#666;background-color:#fff5a9;">outont> 11,000 people ont style="color:#666;background-color:#fff5a9;">outont> of approximately 28,000 infected had died as a result.Officials have been working on the development of an ebola vaccine for years; an experimental one entered testing in Guinea in 2016, showing effic

vaccination: the best return on investment

Photo-illustration: Stuart Bradford
Death due to infectious diseases in infancy and childhood remains perhaps the cruelest fate in the modern world and one of the most preventable. Measures needed to minimize this untimely mortality cannot be ranked as to their importance: Clean drinking water and adequate nutrition are as important as disease prevention and proper sanitation. But if you judge them by their benefit-cost ratios, ont style="color:#666;background-color:#fff5a9;">vaccinationont> is the clear winner.Modern ont style="color:#666;background-color:#fff5a9;">vaccinationont> dates back to the 18th century, when Edward Jenner introduced it against ont style="color:#666;background-color:#fff5a9;">smallpoxont>. Vaccines against cholera, anthrax, and plague were added before the First World War, and others against tuberculosis, tetanus, and diphtheria before the Second. The great postwar breakthroughs included vaccines against pertussis and

new breakthrough paving the way for universal ebola therapeutic

Ebola photomicrograph. Credit: The University of Texas Medical Branch at GalvestonA new collaborative study has identified and studied Ebola antibodies ont style="color:#666;background-color:#fff5a9;">thatont> could be used to design universal therapeutics ont style="color:#666;background-color:#fff5a9;">thatont> are effective against many different Ebola species. The findings were recently published in Nature Microbiology.
The Ebola virus causes a severe illness with high mortality rates in humans. Several strategies have been developed to treat Ebola infection, including ZMapp, which has been shown to be effective in non-human primates and has been used under compassionate-treatment protocols in humans."The trouble with ZMapp is ont style="color:#666;background-color:#fff5a9;">thatont> although it is effective against the Ebola species ont style="color:#666;background-color:#fff5a9;">thatont> was largely responsible for the last Ebola ont style="color:#666;background-color:#fff5a9;">outont>break, it does not neutralize other Ebola species, inclu

new breakthrough paving the way for universal ebola therapeutic

IMAGE: This is an Ebola photomicrograph.
view more Credit: The University of Texas Medical Branch at GalvestonGALVESTON, Texas -A new collaborative study has identified and studied Ebola antibodies ont style="color:#666;background-color:#fff5a9;">thatont> could be used to design universal therapeutics ont style="color:#666;background-color:#fff5a9;">thatont> are effective against many different Ebola species. The findings were recently published in Nature Microbiology.The Ebola virus causes a severe illness with high mortality rates in humans. Several strategies have been developed to treat Ebola infection, including ZMapp, which has been shown to be effective in non-human primates and has been used under compassionate-treatment protocols in humans. "The trouble with ZMapp is ont style="color:#666;background-color:#fff5a9;">thatont> although it is effective against the Ebola species ont style="color:#666;background-color:#fff5a9;">thatont> was largely responsible for the last Ebola ont style="color:#666;background-color:#fff5a9;">outont>break, it

new breakthrough paving the way for universal ebola therapeutic

A new collaborative study has identified and studied Ebola antibodies ont style="color:#666;background-color:#fff5a9;">thatont> could be used to design universal therapeutics ont style="color:#666;background-color:#fff5a9;">thatont> are effective against many different Ebola species. The findings were recently published in Nature Microbiology.

presstv-dr congo to begin ebola vaccination on monday

Health workers in Democratic Republic of Congo will begin a ont style="color:#666;background-color:#fff5a9;">vaccinationont> campaign on Monday aimed at containing an ont style="color:#666;background-color:#fff5a9;">outont>break of the deadly Ebola virus, a spokeswoman for the health ministry said on Sunday.Jessica Ilunga said ont style="color:#666;background-color:#fff5a9;">thatont> 4,000 doses of vaccine were shipped on Saturday to the city of Mbandaka, which last week registered its first cases of the disease in an urban area since the ont style="color:#666;background-color:#fff5a9;">outont>break was declared earlier this month.World Health Organization (WHO) medical supplies to combat the Ebola virus are seen packed in crates at the airport in Mbandaka, Democratic Republic of Congo May 19, 2018. (Photo by Reuters)The ont style="color:#666;background-color:#fff5a9;">outont>break is Congo's ninth since the disease made its first known appearance in the 1970s. The cases in Mbandaka, a port city on the Congo river, have raised concerns ont style="color:#666;background-color:#fff5a9;">thatont> the viru

university of guelph researchers reveal new way to potentially fight ebola

More than 11,000 people died during the Ebola ont style="color:#666;background-color:#fff5a9;">outont>break in West Africa from 2013-16, demonstrating both the deadly nature of the virus and the limitations of the medication used to fight it.Now, University of Guelph researchers have shown ont style="color:#666;background-color:#fff5a9;">thatont> an innovative antibody delivery ont style="color:#666;background-color:#fff5a9;">methodont> could offer an effective way to prevent and treat Ebola infection."Our goal is to make an antibody-based therapy ont style="color:#666;background-color:#fff5a9;">thatont> can protect against all strains of Ebola, and potentially Marburg virus, as well," says Prof. Sarah Wootton, Department of Pathobiology, who, along with PhD student Laura van Lieshont style="color:#666;background-color:#fff5a9;">outont>, found a new way to fight Ebola. "It would be used to stop the spread of the virus in ont style="color:#666;background-color:#fff5a9;">outont>break situations."Wootton says monoclonal antibody therapies (mAbs) hold promise for the treatment of Ebola virus infections. B

experimental ebola vaccine to be used in new dr congo outbreak

The head of the World Health Organization said Sunday there has been another reported case of Ebola in the Democratic Republic of Congo and ont style="color:#666;background-color:#fff5a9;">thatont> an experimental vaccine to fight the disease is expected to become available in the country this week.Doctor Tedros Adhanom Ghebreyesus, on a two-visit to DR Congo, said the suspected new case was in Bikoro, at the centre of the latest Ebola ont style="color:#666;background-color:#fff5a9;">outont>break in the country's northwest, where so far 18 people have died.It brings to 35 the number of reported cases, including two confirmed, according to the WHO tally.The WHO is planning to begin a ont style="color:#666;background-color:#fff5a9;">vaccinationont> campaign in the area, near the border with the Republic of Congo, using an available stockpile of an experimental vaccine.RELATED READING"The vaccines are going to arrive on Wednesday or Thursday. We ha

lessons from ebola: new approach improves disease outbreak management

IMAGE: This is a colorized transmission electron micrograph of an Ebola virus virion, created by CDC microbiologist Frederick A. Murphy.
view more Credit: CDCA new approach to information gathering could allow scientists to quickly identify the most effective way to manage a disease ont style="color:#666;background-color:#fff5a9;">outont>break, an advance ont style="color:#666;background-color:#fff5a9;">thatont> could save lives. Developed by an international team of researchers led by Penn State scientists using insights from the 2014 Ebola ont style="color:#666;background-color:#fff5a9;">outont>break, the ont style="color:#666;background-color:#fff5a9;">methodont> pinpoints critical pieces of missing information required to improve management decisions during an ont style="color:#666;background-color:#fff5a9;">outont>break. A paper describing the approach appears the week of May 15, 2017, in the journal Proceedings of the National Academy of Sciences. "When a disease ont style="color:#666;background-color:#fff5a9;">outont>break happens, there is a lot of information ont style="color:#666;background-color:#fff5a9;">thatont> you just don't know: who w

célébration en guinée du succès du vaccin anti-ebola - guinea

«Le monde est bien mieux préparé s’il devait y avoir une nouvelle flambée d’Ebola», a déclaré aujourd’hui le Dr Margaret Chan, Directeur général de l’Organisation mondiale de la Santé, lors d’un évènement célébrant la contribution des gouvernements et des populations des 3 pays les plus touchés pour endiguer l’épidémie d’Ebola en 2014-2015.Le Dr Chan s’est jointe au Président de la République de Guinée, le Professeur Alpha Condé, au ministre de la Santé, le Dr Abdourahmane Diallo, et aux représentants des gouvernements du Libéria et de la Sierra Leone pour célébrer la réussite de la mise au point du premier vaccin mondial contre le virus Ebola. Le Dr Matshidiso Moeti, Directeur du Bureau régional de l’OMS pour l’Afrique, était également présente.«Nous devons cette réussite vraiment remarqu

with cdc cuts, could we handle another crisis like ebola?

copied!Reid Wilson talks with Chuck on his new book "Epidemic," on the Ebola ont style="color:#666;background-color:#fff5a9;">outont>break and the global response.Mar.30.2018

researchers inhibit ebola virus | eurekalert! science news

A single enzyme. That is all the researchers behind a new study need to manipulate to prevent the feared Ebola virus from spreading. Because with the enzyme they also take away the virus' ability to copy itself and thus produce more virus particles and more infection.The study has been published in the scientific journal Molecular Cell and was conducted by researchers from the University of Copenhagen and Phillips Universität Marburg in Germany.'When the Ebola virus enters the human cell, its only purpose is to copy itself, fast. First it must copy all its proteins, then its genetic material. But by inhibiting a specific enzyme we rob the Ebola virus of its ability to copy itself. And ont style="color:#666;background-color:#fff5a9;">thatont> may potentially prevent an Ebola infection from spreading', says Professor Jakob Nilsson from the Nov

red cross: $6 million for ebola fight stolen through fraud - wane-tv fort wayne

In this Friday, Jan. 15, 2016 file photo, people pass a banner reading 'STOP EBOLA' forming part of Sierra Leone's Ebola free campaign in the city of Freetown, Sierra Leone. Fraud by Red Cross workers and others wasted more than $6 million meant to fight the deadly Ebola ont style="color:#666;background-color:#fff5a9;">outont>break in West Africa, the organization confirmed Saturday, Nov. 4, 2017.Start the conversation, or Read more at WANE-TV Fort Wayne.

why the timing of your flu shot is critical

Timing is everything, especially when it comes to getting the flu shot.The Royal Australian College of General Practitioners (RACGP) says the timing of influenza ont style="color:#666;background-color:#fff5a9;">vaccinationont> is critical to ensuring patients have the highest level of protection when the flu season arrives.Rushing ont style="color:#666;background-color:#fff5a9;">outont> to getting the flu ont style="color:#666;background-color:#fff5a9;">vaccinationont> too early may put people at serious risk, warns RACGP President Dr Bastian Seidel.Related reading"Typically, flu season affects Australia from June to September, with the peak being August," Dr Seidel said."Recent evidence suggests ont style="color:#666;background-color:#fff5a9;">thatont> protection following flu ont style="color:#666;background-color:#fff5a9;">vaccinationont> may begin to wear off after three to four months, so timing of ont style="color:#666;background-color:#fff5a9;">vaccinationont> is critical," he said.Concerned some vaccine providers are already advising patients to receive the flu ont style="color:#666;background-color:#fff5a9;">vaccinationont>, Australians are enc

dubious stem cell clinic got hold of smallpox vaccine. fda just took it away

Enlarge/ A syringe of cells prepared for stem cell therapies Getty | The Washington PostShare this storyThe Food and Drug Administration just put dubious stem cell clinics on notice.The agency announced plans on Monday for new policies and enforcement efforts to stamp ont style="color:#666;background-color:#fff5a9;">outont> what it called “unscrupulous actors” peddling unproven, potentially dangerous, and often expensive stem cell therapies—including a bizarre and troubling instance involving ont style="color:#666;background-color:#fff5a9;">smallpoxont> vaccine.As an initial demonstration of its harder stance, the agency ont style="color:#666;background-color:#fff5a9;">todayont> posted information on two enforcement efforts. One was a warning letter to a Florida stem cell clinic ont style="color:#666;background-color:#fff5a9;">thatont> had posed as legitimate clinical research and ended up blinding three patients after injecting stem cells directly into their eyeballs. The other was a concerning a

en république démocratique du congo, l’épidémie d’ebola inquiète

L’épidémie Ebola est de retour en République Démocratique du Congo. Le gouvernement congolais a annoncé samedi 19 mai le démarrage lundi d’une campagne (RDC) de ont style="color:#666;background-color:#fff5a9;">vaccinationont> contre le virus dans la province de l’Equateur, au nord-ouest de la RDC.Le ministère congolais de la santé a fait savoir samedi que « trois nouveaux » cas ont été détectés, portant à 43 le nombre de cas présentant des symptômes de la maladie. L’épidémie a fait 25 morts, selon l’Organisation mondiale de la santé (OMS). Vendredi, le gouvernement avait annoncé avoir activé le plan de riposte contre cette épidémie « de portée nationale et internationale » tandis que l’OMS a considéré que l’épidémie actuelle ne constituait pas une urgence de « portée mondiale ».

ebola detected in semen of survivors two years after infection

IMAGE: This is David Wohl, M.D.
view more Credit: David WohlChapel Hill, N.C. - Ebola virus RNA can persist in the semen of survivors more than two years after the onset of infection researchers at the University of North Carolina at Chapel Hill have found. The research team, which included investigators from Ohio-based Clinical Research Management and the ELWA Hospital in Liberia also observed the detection of Ebola virus RNA in the semen of men who had previously had a negative test of their semen in some cases. These findings led the study team to suggest revision of the 2016 World Health Organization guidelines relating to the sexual transmission of Ebola, which calls for men who survive Ebola virus disease (EVD) to undertake measures such as abstinence and the use of condoms for at

ebola survivors have a 'unique' retinal scar

IMAGE: These are composite scanning laser ophthalmoscope retinal images showing type 6 Ebola peripapillary or peripheral lesions, observed following the anatomic distribution of the ganglion cell axon (retinal nerve fiber layer),...
view more Credit: University of LiverpoolResearchers from the University of Liverpool have conducted a study of Ebola survivors to determine if the virus has any specific effects on the back on the eye using an ultra widefield retinal camera.To find ont style="color:#666;background-color:#fff5a9;">outont> more abont style="color:#666;background-color:#fff5a9;">outont> the broad-ranging symptoms of Post Ebola Syndrome (PES), a clinical research team led by Dr Janet Scott and Dr Calum Semple, from the University's Institute of Translational Medicine, assessed survivors discharged from the Ebola Treatment Unit at the 34th Regiment Military Hospital in Freetown, Sier

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